The importance of Observational Therapeutics in the progress of Metering Tray medicine has been neglected in the current era of the hierarchal position imparted to Randomized Controlled Trials (RCTs) for new drug discovery and practice of evidence-based medicine.There is a need to reflect on the reason for many new drugs being withdrawn during post
Isolated lateral compartment arthritis or focal chondral defects in the setting of genu valgum in young, active individuals can be treated with a varus-producing distal femoral osteotomy Litter-Robot 4 with or without cartilage treatment.Both medial closing-wedge and lateral opening-wedge techniques have been described, with neither demonstrating c
Abstract.In the downstream part of the spillway building, especially in the flood way, occurs Mini Helmet phenomenon of changing flow conditions from super critical to sub critical which causes a hydraulic jump and used by energy absorbers to reduce flow energy.The hydraulic jump in the floodway causes scouring of the bottom, particularly in the un
Abstract The Food and Drug Administration (FDA) has approved vaccines designed by GSK, copyright and Moderna to protect high-risk populations against respiratory syncytial virus (RSV).These vaccines employ the pre-fusion F (pre-F) protein as the immunogen.In this study, we explored an mRNA vaccine based on a modified pre-F protein called LC2DM-lipi